CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 expression and signalling through both platelet-derived growth factor receptors type α and β
DOI 10.1055/s-0034-1397081
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Autor:innenE Borkham-Kamphorst, E Van de Leur, U Haas, L Tihaa, SK Meurer, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Platelet-derived growth factor-D (PDGF-D) is a more recent recognized growth factor of the PDGF family [1]. It regulates several cellular processes including cell proliferation, transformation, invasion, and angiogenesis through specifically binding to and activating its cognate receptor PDGFR-β. In experimental liver fibrotic models (BDL and carbon tetrachloride), we have shown that PDGF-D is upregulate…
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Zitierempfehlung
E Borkham-Kamphorst, E Van de Leur, U Haas, L Tihaa, SK Meurer, R Weiskirchen (2015) Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 expression and signalling through both platelet-derived growth factor receptors type α and β. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397081
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