CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The extracellular proteinase Expi/Wfdc18 in liver damage and tumour development: A new connection between inflammation, fibrogenesis and malignant growth
DOI 10.1055/s-0034-1397088
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Nachweis in CareLit
Autor:innenR Liebe, R Hall, E Burgermeister, M Ebert, F Lammert, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Recently we have identified quantitative trait loci (QTLs) that determine susceptibility to TGF-beta signalling in mouse hepatocytes in vitro and fibrogenesis in vivo (Liebe et al. Physiol Genomics 2013). Expi/Wfdc18 candidacy was identified by eQTL and DNA variant analyses. Expi/Wfdc18 knockout animals showed decreased hepatic collagen contents following 6 weeks of CCl4 challenge. Methods: To assess t…
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Zitierempfehlung
R Liebe, R Hall, E Burgermeister, M Ebert, F Lammert, S Dooley (2015) The extracellular proteinase Expi/Wfdc18 in liver damage and tumour development: A new connection between inflammation, fibrogenesis and malignant growth. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397088
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