CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Investigations on acetaminophen-induced liver injury using an ex-vivo perfusion model with human liver sections
DOI 10.1055/s-0034-1397109
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Autor:innenT Schreiter, JP Sowa, S Sydor, J Treckmann, G Kaiser, KH Strucksberg, HA Baba, RK Gieseler, G Gerken, A Canbay
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: A perfusion system for human liver sections able to keep hepatic functionality for up to 30 hours was applied to study liver damage mediated by acetaminophen (APAP) in a human tissue based model. Methods: Perfusions were performed for 30 hours and hourly taken samples from the perfusate were analyzed for markers of general metabolism, hepatic synthesis capacity and liver cell damage. APAP was added aft…
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Zitierempfehlung
T Schreiter, JP Sowa, S Sydor, J Treckmann, G Kaiser, KH Strucksberg, HA Baba, RK Gieseler, G Gerken, A Canbay (2015) Investigations on acetaminophen-induced liver injury using an ex-vivo perfusion model with human liver sections. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397109
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