CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis
DOI 10.1055/s-0034-1397134
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Nachweis in CareLit
Autor:innenA Mahli, M Saugspier, WE Thasler, M Müller, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Preoperative chemotherapy for hepatic resection of colorectal liver metastases is associated with the development of chemotherapy-associated steatohepatitis (CASH) which increases the risk of perioperative morbidity and mortality. The aim of this study was to unravel the molecular mechanisms of this phenomenon. Methods and Results: Initially, we determined the dose-range in which irinotecan treatment did not affect…
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Zitierempfehlung
A Mahli, M Saugspier, WE Thasler, M Müller, C Hellerbrand (2015) ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397134
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