CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Xenobiotic-dependent induction of the tricarboxylate carrier Slc13a5 in primary cultures of rat hepatocytes
DOI 10.1055/s-0034-1397151
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Autor:innenF Neuschäfer-Rube, S Lieske, AL Birkenfeld, GP Püschel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The tricarboxylate carrier Slc13a5 (mINDY) is an active transporter that mediates concentrative uptake of citrate in symport with sodium ions across the plasma membrane of cells. In mammals, it is expressed predominantly in hepatocytes and appears to contribute to the cytosolic citrate homeostasis. Citrate is an important intermediate and regulator of fatty acid synthesis. Accordingly, knock down of the…
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Zitierempfehlung
F Neuschäfer-Rube, S Lieske, AL Birkenfeld, GP Püschel (2015) Xenobiotic-dependent induction of the tricarboxylate carrier Slc13a5 in primary cultures of rat hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397151
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