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Comprehensive analysis of informative target disease relevant nuclear genes and the whole mitochondrial genome in hepatocellular carcinoma by Multiplex PCR and Ultra-Deep Sequencing

W Amer, A Quaas, H Eischeid, C Vollbrecht, U Koitzsch, R Büttner, U Drebber, M Odenthal · Zeitschrift für Gastroenterologie · Ausgabe 01/2015

DOI 10.1055/s-0034-1397153

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Autor:innenW Amer, A Quaas, H Eischeid, C Vollbrecht, U Koitzsch, R Büttner, U Drebber, M Odenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Hepatocellular carcinoma (HCC) are highly malignant tumors triggered by a wide variety of genetic alterations. Importantly, they show multicentric occurrence characterized by a nodule-in-nodule pattern. In the present study, we investigate the occurrence of disease related nuclear mutations and whole mitochondrial genomic variants by a comprehensive ultra-deep sequencing approach as a novel tool for hepatocellular c…

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W Amer, A Quaas, H Eischeid, C Vollbrecht, U Koitzsch, R Büttner, U Drebber, M Odenthal (2015) Comprehensive analysis of informative target disease relevant nuclear genes and the whole mitochondrial genome in hepatocellular carcinoma by Multiplex PCR and Ultra-Deep Sequencing. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397153

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