CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Application of mathematical modelling to assess the functional importance of HIF1A for hepatoma biology
DOI 10.1055/s-0034-1397159
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Autor:innenA Kettelhake, N Berndt, O Vvedenskaya, G Mastrobuoni, C Bielow, S Kempa, HG Holzhütter, T Cramer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Liver cancer is becoming a major health problem in western societies due to constantly rising incidence and loss of effective long-term treatment options. HIF1A is frequently overexpressed in human cancers as well as murine tumor models and considered to be an attractive target for innovative cancer therapy. While hepatoma shows evidence for an activated hypoxic response, the functional importance of HIF1A for hepat…
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Zitierempfehlung
A Kettelhake, N Berndt, O Vvedenskaya, G Mastrobuoni, C Bielow, S Kempa, HG Holzhütter, T Cramer (2015) Application of mathematical modelling to assess the functional importance of HIF1A for hepatoma biology. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397159
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