CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Array-based gene expression analysis of M1/M2-polarized macrophages during treatment with multi-kinase inhibitor Sorafenib
DOI 10.1055/s-0034-1397160
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Nachweis in CareLit
Autor:innenMF Sprinzl, J Marquardt, B Brigitte, A Weinmann, H Lang, PR Galle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Multi-kinase inhibitor Sorafenib is the only approved systemic treatment for hepatocellular carcinoma (HCC) and also exerts modulation of tumor-associated macrophages (TAM), enhancing tumor-directed immune responses. Aiming for a better understanding of these effects we searched for gene expression signatures following Sorafenib treatment of cultured macrophages with a classical (M1) or an alternative TA…
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Zitierempfehlung
MF Sprinzl, J Marquardt, B Brigitte, A Weinmann, H Lang, PR Galle (2015) Array-based gene expression analysis of M1/M2-polarized macrophages during treatment with multi-kinase inhibitor Sorafenib. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397160
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