CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cyclin E1 expression level determines the anti-proliferative response of the pharmacological Cdk2 inhibitor Roscovitine in hepatoma cells and in the liver
DOI 10.1055/s-0034-1397163
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Nachweis in CareLit
Autor:innenYA Nevzorova, W Hu, U Haas, N Hoeltke, C Trautwein, C Liedtke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: The cyclin-dependent kinase inhibitor Roscovitine (Rosc) has been regarded as a promising anti-cancer agent. However, the anti-proliferative effects of Rosc in hepatoma cells and in the liver are currently unknown and were investigated in the present study to elucidate if Rosc could be a therapeutic option for the treatment of HCC. Methods: The anti-proliferative and pro-apoptotic properties of Ro…
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Zitierempfehlung
YA Nevzorova, W Hu, U Haas, N Hoeltke, C Trautwein, C Liedtke (2015) Cyclin E1 expression level determines the anti-proliferative response of the pharmacological Cdk2 inhibitor Roscovitine in hepatoma cells and in the liver. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397163
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