CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Integration of exome sequencing and in vivo RNAi screening identifies new cancer genes in hepatocellular carcinoma
DOI 10.1055/s-0034-1397180
Bibliografische Angaben
Nachweis in CareLit
Autor:innenO Neumann, T Wüstefeld, R Pellegrino, R Geffers, P Schirmacher, L Zender, T Longerich
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The recent improvements in the field of sequencing technologies facilitated profiling of whole (tumor) genomes, while in vivo RNAi screening allows for the detection and validation of new cancer genes in an unbiased fashion. Here we combined whole exomic next generation sequencing (NGS) of a single case of human hepatocellular carcinoma with in vivo RNAi screening to identify new protumorigenic driver genes of hepat…
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Zitierempfehlung
O Neumann, T Wüstefeld, R Pellegrino, R Geffers, P Schirmacher, L Zender, T Longerich (2015) Integration of exome sequencing and in vivo RNAi screening identifies new cancer genes in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397180
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