CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model
DOI 10.1055/s-0034-1397182
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Autor:innenFJ Cubero, M Hatting, M Spannbauer, J Peng, W Hu, M Al Masaoudi, G Sellge, N Gassler, C Liedtke, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aim: Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that IL-6/gp130-dependent signaling plays a fundamental role in liver carcinogenesis. Thus, in the present study we aimed to investigate the role of gp130 in hepatocytes for the initiation and progression of HCC. Methods: Hepatocyte-specific gp130 knockout mic…
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Zitierempfehlung
FJ Cubero, M Hatting, M Spannbauer, J Peng, W Hu, M Al Masaoudi, G Sellge, N Gassler, C Liedtke, C Trautwein (2015) Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397182
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