CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
SKP2 cooperates with N-Ras or AKT to induce liver tumor development in the mouse
DOI 10.1055/s-0034-1397199
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Autor:innenDF Calvisi, S Delogu, A Cigliano, K Utpatel, M Sini, T Longerich, N Waldburger, S Ribback, F Dombrowski, X Chen, M Evert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Mounting evidence indicates that S-Phase Kinase-Associated Protein 2 (SKP2) is overexpressed in human hepatocellular carcinoma (HCC). However, the role of SKP2 in hepatocarcinogenesis remains poorly delineated. To elucidate the function(s) of SKP2 in HCC, we stably overexpressed the SKP2 gene in the mouse liver, either alone or in combination with activated forms of N-Ras (N-RasV12), AKT1 (myr-AKT1), or β-catenin (Δ…
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Zitierempfehlung
DF Calvisi, S Delogu, A Cigliano, K Utpatel, M Sini, T Longerich, N Waldburger, S Ribback, F Dombrowski, X Chen, M Evert (2015) SKP2 cooperates with N-Ras or AKT to induce liver tumor development in the mouse. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397199
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