CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Smad7 suppresses HCC development in a DEN induced mouse model
DOI 10.1055/s-0034-1397200
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Nachweis in CareLit
Autor:innenT Feng, J Dzieran, T Maass, A Teufel, S Dooley, NM Meindl-Beinker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Hepatocellular carcinoma (HCC) is the most frequent primary liver tumor. The transforming growth factor-β (TGF-β) signaling pathway plays a critical role in cancer progression. Smad7, a TGF-β target gene, acts as physiological feedback inhibitor of TGF-β and has been found tumorigenic in several tumors. Knowledge about the role of Smad7 in HCC is limited so far. This study investigated the potential ef…
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Zitierempfehlung
T Feng, J Dzieran, T Maass, A Teufel, S Dooley, NM Meindl-Beinker (2015) Smad7 suppresses HCC development in a DEN induced mouse model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397200
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