CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Virotherapy overcomes tumor resistance to PD-1-immunotherapy by broad mutanome-directed T cell responses in mice
DOI 10.1055/s-0034-1397203
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Nachweis in CareLit
Autor:innenN Woller, E Gürlevik, B Fleischmann-Mundt, S Knocke, R Geffers, MP Manns, S Kubicka, F Kühnel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Recently, immune checkpoint blockade has been established as a novel generic immunotherapy of solid tumors. Since pre-existing antitumoral T-cell responses appear to be a precondition for the success of PD-1-immunotherapy, concomitant cancer vaccinations have been investigated but did not affect the clinical outcome. Therefore, we investigated whether localized oncolytic virotherapy is capable to overcome resistance…
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Zitierempfehlung
N Woller, E Gürlevik, B Fleischmann-Mundt, S Knocke, R Geffers, MP Manns, S Kubicka, F Kühnel (2015) Virotherapy overcomes tumor resistance to PD-1-immunotherapy by broad mutanome-directed T cell responses in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397203
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