CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Human liver chimeric mice as a new model of Hepatitis E Virus infection and preclinical drug evaluation
DOI 10.1055/s-0034-1397205
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Gass, T Volz, K Giersch, L Allweiss, A Lohse, J Petersen, S Polywka, S Pischke, M Dandri, M Lütgehetmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: Hepatitis E Virus (HEV) is recognized as important pathogen in developing and industrialized countries leading to acute and chronic infections with considerable morbidity and mortality. Since our knowledge about the molecular biology and pathogenicity of HEV is still rudimental, we employed humanized uPA/SCID/beige (USB) mice to establish a new small animal model of HEV infection. Methods: Homozygous USB…
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Zitierempfehlung
S Gass, T Volz, K Giersch, L Allweiss, A Lohse, J Petersen, S Polywka, S Pischke, M Dandri, M Lütgehetmann (2015) Human liver chimeric mice as a new model of Hepatitis E Virus infection and preclinical drug evaluation. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397205
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