CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Dominance of HLA-B restricted virus-specific CD8+ T cell epitopes in chronic HBV infection
DOI 10.1055/s-0034-1397223
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Nachweis in CareLit
Autor:innenJ Lang, M Kiraithe, R Thimme, C Neumann-Haefelin
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: HBV-specific CD8+ T cells are essential for HBV clearance and are an attractive target for immunotherapeutic intervention. However, the HBV-specific CD8+ T-cell repertoire is poorly characterized. Indeed, < 10 HLA-B restricted HBV-specific CD8+ T cell epitopes are described to date, although recent findings in the field of HIV and HCV infection clearly demonstrate a dominant role of these epitop…
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Zitierempfehlung
J Lang, M Kiraithe, R Thimme, C Neumann-Haefelin (2015) Dominance of HLA-B restricted virus-specific CD8+ T cell epitopes in chronic HBV infection. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397223
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