CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Non-responsiveness to therapeutic tumor vaccination is overcome by functional modulation of myeloid derived suppressor cells
DOI 10.1055/s-0034-1397246
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Autor:innenA Heine, C Llanto, H Gevensleben, L Diehl, N Garbi, P Brossert, PA Knolle, C Kurts, B Höchst
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Therapeutic tumor vaccination represents a promising strategy to induce anti-tumor activity in cancer patients. However, usually only a subpopulation of patients benefits from tumor vaccines, whereas others display continuous tumor growth and metastatic spreading. Here we report a similar observation in a B16 melanoma model. Vaccinating these mice with a model tumor antigen and a combination of adjuvants, i.e. TLR-9…
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Zitierempfehlung
A Heine, C Llanto, H Gevensleben, L Diehl, N Garbi, P Brossert, PA Knolle, C Kurts, B Höchst (2015) Non-responsiveness to therapeutic tumor vaccination is overcome by functional modulation of myeloid derived suppressor cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397246
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