CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Presence of naive-like HBV-specific CD8+ T cells in chronically infected patients despite ongoing viral replication
DOI 10.1055/s-0034-1397248
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Autor:innenA Schuch, C Neumann-Haefelin, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In chronically HBV-infected patients, virus-specific CD8+ T cell responses are rarely detectable ex vivo by conventional tetramer staining. This lack of HBV-specific CD8+ T cell responses may be explained by insufficient priming, T cell exhustion and/or deletion. Here, we set out to address this issue by using new techniques for enumerating virus-specific T cells from human peripheral blood based on the combination…
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Zitierempfehlung
A Schuch, C Neumann-Haefelin, R Thimme (2015) Presence of naive-like HBV-specific CD8+ T cells in chronically infected patients despite ongoing viral replication. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397248
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