CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Viral sequence analysis of the hepatitis B virus core protein reveals CD8 T cell epitopes under reproducible selection pressure
DOI 10.1055/s-0034-1397260
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Autor:innenH Kefalakes, B Budeus, A Walker, C Jochum, G Hilgard, A Heinold, F Heinemann, G Gerken, D Hoffmann, J Timm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Chronic infections with the hepatitis B virus (HBV) are worldwide an enormous public health problem. Effective suppression of viral replication can be achieved with inhibitors of the viral polymerase, however, in most cases lifelong treatment is required to avoid recurrence of viremia. Activation of HBV-specific CD8 T cells by therapeutic vaccination may promote sustained control of viral replication by…
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Zitierempfehlung
H Kefalakes, B Budeus, A Walker, C Jochum, G Hilgard, A Heinold, F Heinemann, G Gerken, D Hoffmann, J Timm (2015) Viral sequence analysis of the hepatitis B virus core protein reveals CD8 T cell epitopes under reproducible selection pressure. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397260
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