CareLit · DOI-Nachweis · Pneumologie
Interferences in myeloid NF-κB signaling affects the inflammatory phenotype after acute smoke exposure and worsens lung damage in a murine model of cigarette smoke-induced emphysema
DOI 10.1055/s-0035-1544600
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Nachweis in CareLit
Autor:innenM Voss, B Wonnenberg, L Wolf, A Kamyschnikow, A Honecker, C Herr, R Bals, C Beisswenger
ZeitschriftPneumologie
Ausgabe02/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cigarette smoking is the main risk factor for the chronic obstructive pulmonary disease (COPD). It was the aim of this study to examine the function of myeloid cell nuclear factor-κB (NF-κB) in cigarette smoke (CS) induced lung inflammation and lung damage. We exposed wild type mice and mice deficient for myeloid RelA/p65 or myeloid IκBα to acute or chronic CS. Numbers of macrophages were increased in RelA/p65-defic…
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Zitierempfehlung
M Voss, B Wonnenberg, L Wolf, A Kamyschnikow, A Honecker, C Herr, R Bals, C Beisswenger (2015) Interferences in myeloid NF-κB signaling affects the inflammatory phenotype after acute smoke exposure and worsens lung damage in a murine model of cigarette smoke-induced emphysema. Pneumologie (02). https://doi.org/10.1055/s-0035-1544600
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