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Reduction in disease progression with nintedanib in the INPULSIS™ trials

M Kreuter, V Cottin, H Taniguchi, HR Collard, L Richeldi, S Stowasser, I Tschoepe, R Schlenker-Herceg, G Raghu · Pneumologie · Ausgabe 02/2015

DOI 10.1055/s-0035-1544832

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Autor:innenM Kreuter, V Cottin, H Taniguchi, HR Collard, L Richeldi, S Stowasser, I Tschoepe, R Schlenker-Herceg, G Raghu
ZeitschriftPneumologie
Ausgabe02/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Nintedanib, an intracellular inhibitor of tyrosine kinases, is in development for the treatment of idiopathic pulmonary fibrosis (IPF). The INPULSIS™ trials were two replicate 52-week, randomized, double-blind, placebo-controlled Phase III trials that investigated the efficacy and safety of nintedanib 150 mg twice daily in 1066 patients with IPF. Declines in forced vital capacity (FVC) % predicted of > 5…

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Zitierempfehlung

M Kreuter, V Cottin, H Taniguchi, HR Collard, L Richeldi, S Stowasser, I Tschoepe, R Schlenker-Herceg, G Raghu (2015) Reduction in disease progression with nintedanib in the INPULSIS™ trials. Pneumologie (02). https://doi.org/10.1055/s-0035-1544832

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