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Effect of baseline emphysema on reduction in FVC decline with nintedanib in the INPULSIS™ trials

M Pfeifer, V Cottin, H Taniguchi, L Richeldi, HR Collard, M Kaye, DM Hansell, Z Bailes, R Schlenker-Herceg, G Raghu · Pneumologie · Ausgabe 02/2015

DOI 10.1055/s-0035-1544834

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Autor:innenM Pfeifer, V Cottin, H Taniguchi, L Richeldi, HR Collard, M Kaye, DM Hansell, Z Bailes, R Schlenker-Herceg, G Raghu
ZeitschriftPneumologie
Ausgabe02/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: The INPULSIS™ trials were two replicate randomized, placebo-controlled, 52-week Phase III trials that assessed the efficacy and safety of nintedanib 150 mg twice daily in patients with IPF. In both trials, nintedanib slowed disease progression by significantly reducing the annual rate of decline in forced vital capacity (FVC), the primary endpoint, compared with placebo. Methods: A post-hoc subgroup anal…

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Zitierempfehlung

M Pfeifer, V Cottin, H Taniguchi, L Richeldi, HR Collard, M Kaye, DM Hansell, Z Bailes, R Schlenker-Herceg, G Raghu (2015) Effect of baseline emphysema on reduction in FVC decline with nintedanib in the INPULSIS™ trials. Pneumologie (02). https://doi.org/10.1055/s-0035-1544834

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