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Dectin-1 Is Expressed in Human Lung and Mediates the Proinflammatory Immune Response to Nontypeable Haemophilus influenzae

KA Heyl, TE Klassert, A Heinrich, MM Müller, E Klaile, H Dienemann, C Grünewald, R Bals, BB Singer, H Slevogt · Pneumologie · Ausgabe 02/2015

DOI 10.1055/s-0035-1544861

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Autor:innenKA Heyl, TE Klassert, A Heinrich, MM Müller, E Klaile, H Dienemann, C Grünewald, R Bals, BB Singer, H Slevogt
ZeitschriftPneumologie
Ausgabe02/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The C-type lectin receptor Dectin-1 is expressed mainly on myeloid cells mediating the immune response targeting respiratory pathogens such as Aspergillus fumigatus and Mycobacterium tuberculosis. The pulmonary epithelium serves as an important interface for interactions between these pathogens and the respiratory tract. Therefore, we analyzed the expression pattern of Dectin-1 in the human lung. Immunohistochemical…

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KA Heyl, TE Klassert, A Heinrich, MM Müller, E Klaile, H Dienemann, C Grünewald, R Bals, BB Singer, H Slevogt (2015) Dectin-1 Is Expressed in Human Lung and Mediates the Proinflammatory Immune Response to Nontypeable Haemophilus influenzae. Pneumologie (02). https://doi.org/10.1055/s-0035-1544861

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