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Effect of baseline FVC on decline in lung function with nintedanib: results from the INPULSIS™ trials

U Costabel, Y Inoue, L Richeldi, HR Collard, S Stowasser, I Tschoepe, A Azuma · Pneumologie · Ausgabe 02/2015

DOI 10.1055/s-0035-1544867

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Autor:innenU Costabel, Y Inoue, L Richeldi, HR Collard, S Stowasser, I Tschoepe, A Azuma
ZeitschriftPneumologie
Ausgabe02/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Nintedanib, an intracellular inhibitor of tyrosine kinases, is in development for the treatment of idiopathic pulmonary fibrosis (IPF). The INPULSIS™ trials were two replicate randomized, double-blind, placebo-controlled, 52-week Phase III trials that assessed the efficacy and safety of nintedanib 150 mg twice daily in patients with IPF. The primary endpoint was the annual rate of decline in forced vital…

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U Costabel, Y Inoue, L Richeldi, HR Collard, S Stowasser, I Tschoepe, A Azuma (2015) Effect of baseline FVC on decline in lung function with nintedanib: results from the INPULSIS™ trials. Pneumologie (02). https://doi.org/10.1055/s-0035-1544867

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