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Molecular heterogeneity of mucin as a potential biomarker for inflammatory airway disorders: identification of detection reagents

T Krause, K Ramaker, H Sinnecker, A Frey · Pneumologie · Ausgabe 02/2015

DOI 10.1055/s-0035-1544879

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Autor:innenT Krause, K Ramaker, H Sinnecker, A Frey
ZeitschriftPneumologie
Ausgabe02/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Evidence accumulates that airway mucins harbour disease-related alterations in their composition and glycosylation. For cystic fibrosis patients a correlation between the severity of airway infections and an increase in mucin sialylation was described. A similar change in glycosylation was observed upon the induction of asthma in experimental animals. In case of COPD the ratio of the two major airway mucins MUC5AC a…

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T Krause, K Ramaker, H Sinnecker, A Frey (2015) Molecular heterogeneity of mucin as a potential biomarker for inflammatory airway disorders: identification of detection reagents. Pneumologie (02). https://doi.org/10.1055/s-0035-1544879

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