CareLit · DOI-Nachweis · Pneumologie
Role of arginase 1 in lung protective immunity against Streptococcus pneumoniae infection in mice
DOI 10.1055/s-0035-1548634
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Nachweis in CareLit
Autor:innenS Knippenberg, C Brumshagen, F Aschenbrenner, T Welte, UA Maus
ZeitschriftPneumologie
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Type 2 helper cell (Th2) dominated chronic lung diseases like asthma are characterized by an increased risk for bacterial lung infections. However, the underlying mechanisms are poorly defined. Arginase 1 (Arg1) has been suggested to play an important role in the pathophysiology of asthma, and is rapidly induced in lung macrophages by Th2 cytokines, thereby limiting macrophage-derived antimicrobial nit…
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Zitierempfehlung
S Knippenberg, C Brumshagen, F Aschenbrenner, T Welte, UA Maus (2015) Role of arginase 1 in lung protective immunity against Streptococcus pneumoniae infection in mice. Pneumologie (04). https://doi.org/10.1055/s-0035-1548634
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