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Legionella in the lung: development of a human ex vivo tissue culture system to study host microbe interactions

S Marwitz, J Jäger, J Tiefenau, J Rasch, O Shevchuk, C Kugler, T Goldmann, M Steinert · Pneumologie · Ausgabe 04/2015

DOI 10.1055/s-0035-1548637

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Autor:innenS Marwitz, J Jäger, J Tiefenau, J Rasch, O Shevchuk, C Kugler, T Goldmann, M Steinert
ZeitschriftPneumologie
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Lung infections with Legionella pneumophila may lead to an aggressive pneumonia with a typical histological phenotype. The majority of current investigations focusses either on the late stages of infections in patients, is limited to cell culture experiments or uses rodent models. Therefore we developed a human ex vivo tissue culture model to study the early events of L. pneumophila. Human tissue explants were stimu…

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S Marwitz, J Jäger, J Tiefenau, J Rasch, O Shevchuk, C Kugler, T Goldmann, M Steinert (2015) Legionella in the lung: development of a human ex vivo tissue culture system to study host microbe interactions. Pneumologie (04). https://doi.org/10.1055/s-0035-1548637

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