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IL-15/IL-15Rα as targets for modulation of autoimmune reactions in central nervous system

MVN Divivier, Z Orinska · Pneumologie · Ausgabe 04/2015

DOI 10.1055/s-0035-1548647

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Autor:innenMVN Divivier, Z Orinska
ZeitschriftPneumologie
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Einleitung: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) that is initiated by CNS-infiltrating self reactive T-cells that recognize myelin antigens. Damage of target tissue is mediated by components of the immune system (e.g.CD8+-T cells). An animal model for MS is Experimental autoimmune encephalomyelitis (EAE) in mice. Differentiation of CD8+-T cells is regulated by IL-15/…

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MVN Divivier, Z Orinska (2015) IL-15/IL-15Rα as targets for modulation of autoimmune reactions in central nervous system. Pneumologie (04). https://doi.org/10.1055/s-0035-1548647

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