CareLit · DOI-Nachweis · Pneumologie
IL-37 requires IL18Rα and SIGIRR/IL-1R8 to ameliorate experimental allergic asthma in mice
DOI 10.1055/s-0035-1548656
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Lunding, S Webering, C Vock, A Schröder, D Raedler, B Schaub, H Fehrenbach, M Wegmann
ZeitschriftPneumologie
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The new cytokine interleukin (IL) 37 has been described as negative regulator of innate immunity. It reduces activation of DCs and the production of pro-inflammatory mediators in murine and human immune cells. Recently, results from the CLARA childhood asthma cohort suggested an impact of IL-37 on human asthma pathogenesis. This study aimed to clarify, whether IL-37 also provides anti-inflammatory effect…
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Zitierempfehlung
L Lunding, S Webering, C Vock, A Schröder, D Raedler, B Schaub, H Fehrenbach, M Wegmann (2015) IL-37 requires IL18Rα and SIGIRR/IL-1R8 to ameliorate experimental allergic asthma in mice. Pneumologie (04). https://doi.org/10.1055/s-0035-1548656
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