CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The macrophage migration inhibitory factor (MIF)/CXCR4 axis regulates migration of bone marrow derived mesenchymal stem cells towards pancreatic ß-cells under lipotoxic conditions
DOI 10.1055/s-0035-1549512
Bibliografische Angaben
Nachweis in CareLit
Autor:innenB Mihic-Necic, S Taromi, C Liu, J Straetener, M Ihle, D Kriedemann, M Hille, AE Mehana, K Laubner, N Perakakis, G Päth, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aim: Mesenchymal stem cells (MSCs) bare the ability to home to sites of injury where they act by secreting angiogenic- and immunomodulatory factors. Previously we demonstrated that human telomerase-immortalised MSCs (hMSC-TERT) migrate towards injured INS-1E ß-cells, where they preserve cellular viability. Here we identify macrophage migration inhibitory factor (MIF) secreted by injured ß-cells as che…
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Zitierempfehlung
B Mihic-Necic, S Taromi, C Liu, J Straetener, M Ihle, D Kriedemann, M Hille, AE Mehana, K Laubner, N Perakakis, G Päth, J Seufert (2015) The macrophage migration inhibitory factor (MIF)/CXCR4 axis regulates migration of bone marrow derived mesenchymal stem cells towards pancreatic ß-cells under lipotoxic conditions. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549512
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