CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The role of TBC1D1 and TBC1D4 in contraction-induced glucose uptake in mouse skeletal muscle
DOI 10.1055/s-0035-1549519
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Nachweis in CareLit
Autor:innenC de Wendt, A Chadt, J Loffing, D Loffing-Cueni, HG Joost, H Al-Hasani
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: The RabGTPase-activating proteins (RabGAPs) TBC1D1 and TBC1D4 (AS160) are key players in AKT- and AMPK-regulated glucose metabolism. The aim of this study is to analyze the contribution of these two homologous proteins to the contraction-mediated glucose uptake and metabolism in skeletal muscle. Methods: TBC1D1/TBC1D4-double-deficient mice (D1/4KO) were generated. Ex vivo muscle contraction was…
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Zitierempfehlung
C de Wendt, A Chadt, J Loffing, D Loffing-Cueni, HG Joost, H Al-Hasani (2015) The role of TBC1D1 and TBC1D4 in contraction-induced glucose uptake in mouse skeletal muscle. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549519
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