CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Adaptor protein APPL1 counteracts streptozotocin-induced diabetes in mice
DOI 10.1055/s-0035-1549558
Bibliografische Angaben
Nachweis in CareLit
Autor:innenZ Chen, A Xu, K Cheng
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The adapter protein APPL1 has been reported for its beneficial role against type 2 diabetes by promoting both secretion and actions of insulin. In this study, we aimed to investigate whether APPL1 plays a protective role in β-cell function in type 1 diabetes Method: Both male 12-week old APPL1 knockout (KO) mice and their wild-type (WT) littermates were treated with 50 mg/kg streptozotocin (STZ) for 5…
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Zitierempfehlung
Z Chen, A Xu, K Cheng (2015) Adaptor protein APPL1 counteracts streptozotocin-induced diabetes in mice. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549558
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