CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
STZ treatment causes depletion of immune cells in sciatic nerve and dorsal root ganglion in mice
DOI 10.1055/s-0035-1549571
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Autor:innenA Hidmark, T Fleming, D Deshpande, S Vittas, PP Nawroth
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Streptozotocin (STZ) treatment is an accepted pharmacological method for the induction of type 1 diabetes in rodent models. Recent publications have shown that STZ induces thermal hyperalgesia in mice, independently of hyperglycemia, and that STZ is neurotoxic in vitro. These findings bring into question the limitations of STZ-induced diabetes as a model for diabetic neuropathy. The aim of this study w…
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Zitierempfehlung
A Hidmark, T Fleming, D Deshpande, S Vittas, PP Nawroth (2015) STZ treatment causes depletion of immune cells in sciatic nerve and dorsal root ganglion in mice. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549571
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