CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Effect of increased glucose on the expression of TLRs in human macrophages: potential mechanism of chronic inflammation in diabetes
DOI 10.1055/s-0035-1549579
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Balduff, K Moganti, F Li, H Klüter, M Harmsen, A Gratchev, J Kzhyshkowska
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Diabetic patients suffer from a chronic inflammation regulated by macrophages. M1 and M2 represent two major directions of macrophage functional polarisation. Toll-like receptors (TLR)-mediated response to exogenous and endogenous factors results in pro-inflammatory activation of macrophages. Increased TLR expression in monocytes is associated with the diabetic inflammation and complications. The aim of our study wa…
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Zitierempfehlung
M Balduff, K Moganti, F Li, H Klüter, M Harmsen, A Gratchev, J Kzhyshkowska (2015) Effect of increased glucose on the expression of TLRs in human macrophages: potential mechanism of chronic inflammation in diabetes. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549579
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