CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Modulation of immune-response in female aP2-Cre ERalpha-knockout mice due to high-fat diet feeding and high estradiol levels
DOI 10.1055/s-0035-1549594
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Nachweis in CareLit
Autor:innenZ Ban, V Benz, R Klopfleisch, G Schuler, S Brix, J Grune, A Foryst-Ludwig, U Kintscher
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Previously reported abnormalities in the reproductive-tract of female adipose-tissue-specific (ap2-Cre) ERα-knockout (ERaKO)-mice were linked with a 40% decrease of ERα-gene-expression in the hypothalamus of these animals, when compared to their control-mice (ERα-floxed;WT). Subsequently, ERaKO-mice showed a pronounced upregulation of estradiol (E2)-plasma levels (KO: 45.9 vs. WT: 19.8pg/ml;p < 0.01) resulting from…
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Zitierempfehlung
Z Ban, V Benz, R Klopfleisch, G Schuler, S Brix, J Grune, A Foryst-Ludwig, U Kintscher (2015) Modulation of immune-response in female aP2-Cre ERalpha-knockout mice due to high-fat diet feeding and high estradiol levels. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549594
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