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The adiponectin paralog CTRP9 but not CTRP7 mediates anti-oxidative effects in adult rat cardiomyocytes through an AMPK, adiponectin receptor and calreticulin dependent mechanism

L Li, D Stumpp, B Siegler, M Micoogullari, B Niemann, M Aslam, H Bugger, H Jakoub, KD Schlüter, RE Silber, S Rohrbach · Diabetologie und Stoffwechsel · Ausgabe 04/2015

DOI 10.1055/s-0035-1549595

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Autor:innenL Li, D Stumpp, B Siegler, M Micoogullari, B Niemann, M Aslam, H Bugger, H Jakoub, KD Schlüter, RE Silber, S Rohrbach
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: The adipokine adiponectin has direct beneficial effects on cardiomyocytes. However, obesity and ageing are characterized by an adiponectin deficit. Recently, a family of adiponectin paralogs, comprising 15 members so far, was discovered and designated as C1q/tumor necrosis factor-alpha-related proteins (CTRPs). While the protective adiponectin actions are well recognized, questions remain unanswered conc…

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L Li, D Stumpp, B Siegler, M Micoogullari, B Niemann, M Aslam, H Bugger, H Jakoub, KD Schlüter, RE Silber, S Rohrbach (2015) The adiponectin paralog CTRP9 but not CTRP7 mediates anti-oxidative effects in adult rat cardiomyocytes through an AMPK, adiponectin receptor and calreticulin dependent mechanism. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549595

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