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DNA 5-Hydroxymethylation in human adipose tissue differs between subcutaneous and visceral adipose tissue depots

K Rohde, M Keller, M Stumvoll, A Dietrich, M Blüher, Y Böttcher · Diabetologie und Stoffwechsel · Ausgabe 04/2015

DOI 10.1055/s-0035-1549600

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Autor:innenK Rohde, M Keller, M Stumvoll, A Dietrich, M Blüher, Y Böttcher
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben

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Background: Epigenetic mechanisms such as DNA methylation at the 5-carbon of cytosine (5-mC) were shown to have tissue specific patterns and play a role in post-transcriptional regulation of gene expression. While 5-mC is well studied, the discovery of a stable intermediate during DNA de-methylation (5-hydroxymethylcytosin (5-hmC)) raises questions about its function and distribution. The aim of this study was to te…

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Zitierempfehlung

K Rohde, M Keller, M Stumvoll, A Dietrich, M Blüher, Y Böttcher (2015) DNA 5-Hydroxymethylation in human adipose tissue differs between subcutaneous and visceral adipose tissue depots. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549600

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