CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Identification of novel susceptibility genes for diabetes- and obesity-related traits in a backcross of obese NZO with lean C3 H mice
DOI 10.1055/s-0035-1549627
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Schallschmidt, S Osthold, Y Schulte, M Damen, T Stermann, A Chadt, H Al-Hasani
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Type 2 diabetes (T2D) in humans is influenced by a combination of hundreds of adipogenic and diabetogenic alleles. In outcross experiments of obese and lean mouse strains, several QTL (Quantitative Trait Loci) for obesity and hyperglycaemia were separated. Mouse models could therefore help to identify several key obesity and diabetes modifier genes. In order to find further disease genes we perf…
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Zitierempfehlung
T Schallschmidt, S Osthold, Y Schulte, M Damen, T Stermann, A Chadt, H Al-Hasani (2015) Identification of novel susceptibility genes for diabetes- and obesity-related traits in a backcross of obese NZO with lean C3 H mice. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549627
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