CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Post-translational control of carnosinase activitiy in diabetes
DOI 10.1055/s-0035-1549687
Bibliografische Angaben
Nachweis in CareLit
Autor:innenV Peters, B Lanthaler, A Amberger, T Fleming, E Forsberg, M Hecker, A Wagner, GF Hoffmann, P Nawroth, J Zschocke, CP Schmitt
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Carnosinase 1 (CN1) contributes to diabetic nephropathy by cleaving histidine-dipeptides which scavenge reactive oxygen and carbonyl species and increase nitric oxide (NO) production. In diabetic mice renal CN1 is increased, the regulatory mechanisms are unknown. Methods: We analysed the in vitro and in vivo regulation of CN1 activity using recombinant and human CN1, and the db/db mouse model of diabetes…
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Zitierempfehlung
V Peters, B Lanthaler, A Amberger, T Fleming, E Forsberg, M Hecker, A Wagner, GF Hoffmann, P Nawroth, J Zschocke, CP Schmitt (2015) Post-translational control of carnosinase activitiy in diabetes. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549687
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