CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Metformin improves intestinal L cell survival in vitro and in vivo
DOI 10.1055/s-0035-1549690
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Iakoubov, PL Brubaker, LM Lauffer
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Glucagon-like peptide-1 (GLP-1) is released from the intestinal L-cell following stimulation by nutrients. Hence, GLP-1-based medication is now available for type 2 diabetes. As previously reported, metformin, an AMP-protein kinase (AMPK) activator, causes increased GLP-1 levels in vivo, but not in vitro. We hypothesized that the increased GLP-1 levels might be associated with enhanced L-cell proliferation and…
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Zitierempfehlung
R Iakoubov, PL Brubaker, LM Lauffer (2015) Metformin improves intestinal L cell survival in vitro and in vivo. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549690
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