CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The role of FOXO1 in palmitate-induced β-cell death
DOI 10.1055/s-0035-1549756
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Nachweis in CareLit
Autor:innenM Panse, F Gerst, G Kaiser, HU Häring, S Ullrich
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aim: The transcription factor FOXO1 has opposing effects in β-cells: On one hand it transmits pro-apoptotic effects under glucolipotoxic conditions, while on the other hand it promotes cell differentiation and insulin secretion under a non-stress environment. It is currently accepted that palmitate mediated lipotoxicity is accompanied with ER stress. However, several observations also indicate that pa…
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Zitierempfehlung
M Panse, F Gerst, G Kaiser, HU Häring, S Ullrich (2015) The role of FOXO1 in palmitate-induced β-cell death. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549756
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