CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Contrasting effects of sulfonylurea and K+ depolarization on insulin and glucagon secretion by perifused mouse islets
DOI 10.1055/s-0035-1549760
Bibliografische Angaben
Nachweis in CareLit
Autor:innenEH Früh, N Görgler, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: In pancreatic beta cells KATP channels couple changes in glucose metabolism to changes in insulin secretion via depolarization of the plasma membrane. In alpha cells, in contrast, where increased glucose levels inhibit hormone secretion, their role is in dispute. Methods: Batches of 50 freshly isolated NMRI mouse islets were perifused with a HEPES-buffered Krebs-Ringer medium (2 mg/ml BSA) satur…
Zitieren
Zitierempfehlung
EH Früh, N Görgler, I Rustenbeck (2015) Contrasting effects of sulfonylurea and K+ depolarization on insulin and glucagon secretion by perifused mouse islets. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549760
Mit CareLit weiterarbeiten