CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Differences in the oxygen consumption pattern suggest that nutrient-induced insulin secretion is differentially regulated in primary mouse islets and MIN6 pseudo-islets
DOI 10.1055/s-0035-1549763
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Nachweis in CareLit
Autor:innenT Schulze, M Morsi, D Brüning, K Schumacher, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: In addition to plasma membrane depolarization metabolic amplification is required for the full extent of nutrient-induced insulin secretion. For metabolomic investigations insulin-secreting cell lines, such as MIN6, are utilized. The relevance of such data is, however, unclear. Methods: All parameters were measured by perifusion of freshly isolated mouse islets or of MIN6 pseudo-islets. The oxyg…
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Zitierempfehlung
T Schulze, M Morsi, D Brüning, K Schumacher, I Rustenbeck (2015) Differences in the oxygen consumption pattern suggest that nutrient-induced insulin secretion is differentially regulated in primary mouse islets and MIN6 pseudo-islets. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549763
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