CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Granule mobility, fusion frequency and stimulated insulin secretion are differentially affected by insulinotropic stimuli
DOI 10.1055/s-0035-1549765
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Nachweis in CareLit
Autor:innenD Brüning, K Schumacher, M Matz, K Baumann, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: The view that insulin granules constitute functionally distinct pools which are sequentially recruited to release insulin has been put into question by new imaging techniques. Here, we characterized the number and mobility of submembrane granules in response to insulinotropic stimuli. Methods: Insulin secretion, cytosolic Ca2+ concentration ([Ca2+]i) and granule mobility in the submembrane space…
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Zitierempfehlung
D Brüning, K Schumacher, M Matz, K Baumann, I Rustenbeck (2015) Granule mobility, fusion frequency and stimulated insulin secretion are differentially affected by insulinotropic stimuli. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549765
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