CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Pyruvate kinase isoenzyme M2 is increased in experimental diabetes and correlates with diabetic neuropathy in patients
DOI 10.1055/s-0035-1549780
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Nachweis in CareLit
Autor:innenS Vittas, TH Fleming, A Hidmark, D Oikonomou, N Volk, S Kopf, PP Nawroth
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Pyruvate kinase (PK) catalyzes the conversion of phosphoenolpyruvate (PEP) to pyruvate as the last step of glycolysis. The two major PK isoforms, PKM1 and PKM2, show different activity levels, with PKM2 being highly expressed in cancer. PK isoforms mRNA expression was investigated in control and diabetic material from human and mouse in order to investigate whether PKM isoforms show differential expres…
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Zitierempfehlung
S Vittas, TH Fleming, A Hidmark, D Oikonomou, N Volk, S Kopf, PP Nawroth (2015) Pyruvate kinase isoenzyme M2 is increased in experimental diabetes and correlates with diabetic neuropathy in patients. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0035-1549780
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