CareLit · DOI-Nachweis · Klinische Pädiatrie
Cardiac side effects of chronic dasatinib (DA) exposure in juvenile growing rats
DOI 10.1055/s-0035-1550237
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Uhlemann, JT Tauer, R Jung, M Suttorp
ZeitschriftKlinische Pädiatrie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Application of DA in adults with CML may lead to adverse cardiac effects (pleural & pericardial effusion, abnormal heart rate, organ hypertrophy). Understanding underlying mechanisms is crucial for the application of DA in pediatrics. Methods: DA was administered chronically [either standard (SD) or high dose (HD)) or intermittently HD (3 days “on”, 4 days “off”] via the drinking water to 4 week (w) old…
Zitieren
Zitierempfehlung
H Uhlemann, JT Tauer, R Jung, M Suttorp (2015) Cardiac side effects of chronic dasatinib (DA) exposure in juvenile growing rats. Klinische Pädiatrie (07). https://doi.org/10.1055/s-0035-1550237
Mit CareLit weiterarbeiten