CareLit · DOI-Nachweis · Klinische Pädiatrie
Incidence and genetic characterization of childhood acute lymphoblastic leukemia with CRLF2 overexpression treated according to the AIEOP-BFM ALL 2009 protocol
DOI 10.1055/s-0035-1550244
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Schmäh, B Fedders, M Zimmermann, E Dagdan, P Dörge, S Bens, A Moericke, J Alten, K Bleckmann, R Siebert, M Schrappe, M Stanulla, G Cario
ZeitschriftKlinische Pädiatrie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Overexpression of the cytokine receptor-like factor 2 (CRLF2) gene in acute lymphoblastic leukemia (ALL) is caused by different aberrations like a deletion juxtaposing CRLF2 with the P2RY8 promoter, by a translocation involving the immunoglobulin heavy chain locus (IGH@), by supernumerary copies of the CRLF2 locus or by not yet identified causes. Several retrospective studies showed that only the presence of the P2R…
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Zitierempfehlung
J Schmäh, B Fedders, M Zimmermann, E Dagdan, P Dörge, S Bens, A Moericke, J Alten, K Bleckmann, R Siebert, M Schrappe, M Stanulla, G Cario (2015) Incidence and genetic characterization of childhood acute lymphoblastic leukemia with CRLF2 overexpression treated according to the AIEOP-BFM ALL 2009 protocol. Klinische Pädiatrie (07). https://doi.org/10.1055/s-0035-1550244
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