CareLit · DOI-Nachweis · Klinische Pädiatrie
A Case of Concordant Twins with Infant ALL and Discordant Clinical Outcome – Part I: the genetic basis – identification of DSC2 as a gene with prognostic impact in infant MLL-rearranged ALL
DOI 10.1055/s-0035-1550248
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Fedders, BS Petersen, A Alsadeq, C Kellner, M Peipp, M Bulduk, T Valerius, R Häsler, J Alten, A Möricke, S Strube, T Wiesel, G Cario, M Schrappe, A Franke, M Stanulla, DM Schewe
ZeitschriftKlinische Pädiatrie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Infant acute lymphoblastic leukemia (ALL) is associated with an unfavorable prognosis due to a high proportion of early relapses. We report on a pair of monozygotic twin sisters diagnosed with ALL (MLL-ENL fusion) in early infancy. Despite good initial treatment responses in both twins, one sister developed very early relapse (Twin A) and succumbed to the disease. The other sister went into continuous complete remis…
Zitieren
Zitierempfehlung
H Fedders, BS Petersen, A Alsadeq, C Kellner, M Peipp, M Bulduk, T Valerius, R Häsler, J Alten, A Möricke, S Strube, T Wiesel, G Cario, M Schrappe, A Franke, M Stanulla, DM Schewe (2015) A Case of Concordant Twins with Infant ALL and Discordant Clinical Outcome – Part I: the genetic basis – identification of DSC2 as a gene with prognostic impact in infant MLL-rearranged ALL. Klinische Pädiatrie (07). https://doi.org/10.1055/s-0035-1550248
Mit CareLit weiterarbeiten