CareLit · DOI-Nachweis · Klinische Pädiatrie
A Case of Concordant Twins with Infant ALL and Discordant Clinical Outcome – Part II: highlights on an immunoescape phenotype as a potential mechanism of disease persistence
DOI 10.1055/s-0035-1550250
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Alsadeq, H Fedders, BS Petersen, C Kellner, M Peipp, M Bulduk, T Valerius, R Häsler, J Alten, A Möricke, S Strube, T Wiesel, G Cario, M Schrappe, A Franke, M Stanulla, DM Schewe
ZeitschriftKlinische Pädiatrie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Acute lymphoblastic leukemia (ALL) in infants is characterized by a high incidence of translocations involving the MLL gene, and is associated with an unfavorable prognosis. Here we investigate a case of monozygotic twin sisters harboring an MLL-ENL fusion. Both sisters had good treatment response at the end of induction. However, Twin A developed an early relapse and succumbed to the disease, whereas Twin B went in…
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Zitierempfehlung
A Alsadeq, H Fedders, BS Petersen, C Kellner, M Peipp, M Bulduk, T Valerius, R Häsler, J Alten, A Möricke, S Strube, T Wiesel, G Cario, M Schrappe, A Franke, M Stanulla, DM Schewe (2015) A Case of Concordant Twins with Infant ALL and Discordant Clinical Outcome – Part II: highlights on an immunoescape phenotype as a potential mechanism of disease persistence. Klinische Pädiatrie (07). https://doi.org/10.1055/s-0035-1550250
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