CareLit · DOI-Nachweis · Klinische Pädiatrie
Prognostic relevance of the expression of genes associated with the P2RY8-CRLF2 fusion in acute lymphoblastic leukemia in childhood
DOI 10.1055/s-0035-1550251
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Buchmann, J Schmäh, M Zimmermann, D Schewe, H Fedders, A Moericke, J Alten, K Bleckmann, M Schrappe, M Stanulla, G Cario
ZeitschriftKlinische Pädiatrie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The cytokine receptor-like factor 2 (CRLF2) gene is overexpressed in a subgroup of precursor B-cell acute lymphoblastic leukemia (pB-ALL) caused by different genetic aberrations. However, only the presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis. Recently, we showed that the presence of the P2RY8-CRLF2 rearrangement is characterized by a distinct transcriptome profiling as detected by ne…
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Zitierempfehlung
S Buchmann, J Schmäh, M Zimmermann, D Schewe, H Fedders, A Moericke, J Alten, K Bleckmann, M Schrappe, M Stanulla, G Cario (2015) Prognostic relevance of the expression of genes associated with the P2RY8-CRLF2 fusion in acute lymphoblastic leukemia in childhood. Klinische Pädiatrie (07). https://doi.org/10.1055/s-0035-1550251
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